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A1762T/G1764A突变通过交替病毒转录基因组来增强HBV复制

Danli Yang1, Jun Zou1,2, Guiwen Guan1

  • 1Department of Microbiology and Infectious Disease Center, School of Basic Medical Sciences, Peking University, Beijing, China.

Journal of medical virology
|September 29, 2023
PubMed
概括

在乙型肝炎病毒基底核心促进体中常见的突变通过调高基因前RNA并创建HNF1α结合位点来增强病毒复制. 这些发现提供了关于慢性HBV感染管理和潜在治疗点的见解.

关键词:
在HBV转录基因组中,基底核促销物突变基底核促销物突变全长度转录基因组测序.乙型肝炎病毒的感染.这就是pgRNA子RNA.

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