相关实验视频
Updated: Jul 15, 2025

07:13
ATAC-Seq Optimization for Cancer Epigenetics Research
Published on: June 30, 2022
4.4K
Q20+纳米孔测序数据恢复了一个高质量的Asticcacaulis sp. 基因组 基因组是基因组的组成部分
Cyrill Hofer1, Seraina Lingenhag2, Lucas Serra Moncadas1
1Department of Plant and Microbial Biology, Limnological Station, University of Zurich, Kilchberg, Switzerland.
Microbiology resource announcements
|September 29, 2023
概括
我们对Asticcacaulis sp.的完整基因组进行了测序. ZE23SCel15,是一个来自苏黎世湖的细菌. 这为微生物生态学和Asticacaulis研究提供了宝贵的基因组资源.
科学领域:
- 微生物学 微生物学
- 基因组学就是基因组学.
- 环境科学 环境科学
背景情况:
- 阿斯蒂卡卡库利斯 (Asticcacaulis) 是一种在水生环境中发现的细菌.
- 了解微生物基因组对于生态研究至关重要.
研究的目的:
- 为了呈现Asticcacaulis sp.的完整基因组序列. ZE23SCel15.15 的时间.
- 为未来的研究提供高质量的基因组组件.
主要方法:
- 孤立的阿斯蒂卡卡库利斯 sp. ZE23SCel15来自苏黎世湖的地表水.
- 高质量的纳米孔测序 (Q20+).
- 基因组的生物信息组合.
主要成果:
- 产生了一个完整的,圆形的基因组组合~3.8 Mb.
- 该基因组的GC含量为56.81%,覆盖面为34×.
- 基因组序列提供了该菌株的全面遗传蓝图.
结论:
- 阿斯蒂卡卡库利斯 (Asticcacaulis sp.) 的基因组 现在可以完全使用ZE23SCel15.
- 这些基因组数据将支持进一步研究Asticcacaulis生物及其在水生生态系统中的作用.
相关概念视频
Genome Annotation and Assembly
18.9K
The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
18.9K
Next-generation Sequencing
89.8K
The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features....
89.8K
Sanger Sequencing
754.7K
DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
754.7K

