在患有和没有精神疾病的患者中,整体和宫癌的生存率
Eva Herweijer1, Jiangrong Wang2, Kejia Hu1
1Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
JAMA network open
|September 29, 2023
概括
被诊断为宫癌的精神疾病患者面临更高的死亡风险. 这凸显了针对这一脆弱患者群体进行有针对性的干预和支持的需要.
科学领域:
- 在瘤学瘤学.
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 患有精神障碍的人体验到健康差异,包括参与查和接种疫苗的比例较低.
- 这一群体也可能从三级癌症预防策略中获得较少的好处.
研究的目的:
- 为了比较子宫癌患者的临床特征和生存结果,有或没有先前的精神障碍诊断.
- 调查精神障碍对宫癌预后的影响.
主要方法:
- 一个瑞典基于人口的队列研究,利用来自多个国家注册的数据 (1978-2018).
- 使用ICD代码识别了宫癌患者和具有先前精神障碍的患者.
- 分析了整体和癌症特异性死亡率,并调整了临床和社会人口统计因素.
主要成果:
- 患有宫癌和先前存在的精神疾病的患者有较高的全因死亡风险 (HR, 1.32) 和宫癌特异性死亡率 (HR, 1.23).
- 根据癌症特征进行调整可以降低这些风险,这表明部分调解.
- 药物滥用,精神疾病或需要住院心理健康护理的患者的死亡风险较高.
结论:
- 以前存在精神障碍的宫癌患者表现出较差的生存结果.
- 这些差异可能部分归因于诊断时的临床和社会人口统计学因素.
- 患有精神障碍的个人需要在第三级宫癌预防工作中集中注意.
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