中的虫虫感染:病理生物学和免疫学管弦乐队
Nusrat Nowrin Shohana1, Sharmin Aqter Rony1, Md Haydar Ali1,2
1Department of Parasitology, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Immunity, inflammation and disease
|September 29, 2023
概括
阿斯卡里迪亚菌感染会伤害,导致肠道病理并影响生产. 主体免疫力,特别是2型免疫力,包括细胞因子和IgY等抗体,在对抗寄生虫方面发挥着至关重要的作用.
科学领域:
- 兽医免疫学 兽医免疫学
- 寄生虫学的寄生虫学
- 禽畜科学 禽畜科学 禽畜科学
背景情况:
- 阿斯卡里迪亚 (Ascaridia galli) 是的主要虫寄生虫,对肉类和蛋生产产生负面影响.
- A. galli 的幼虫阶段主要负责肠道的重大病理.
研究的目的:
- 审查与中阿斯卡里迪亚菌感染相关的免疫学和病理学.
- 阐明宿主的免疫反应机制,以对抗A. galli.
主要方法:
- 进行了全面的文献审查.
- 包括PubMed,Google Scholar和Researchgate在内的在线数据库被用于数据收集.
主要成果:
- A. galli幼虫诱导严重的肠道病理,包括粘液过分,炎症,出血,贫血,腹和营养不良.
- 细胞免疫包括Th-2细胞因子 (IL-4,IL-5,IL-9,IL-13),杯状细胞,GALT,CD8α+ IEL,TCRγδ+ T细胞和TGF-β4.4等.
- 幽默免疫的特点是IgY的产生,年长的 (12周以上) 显示出更好的虫负担减少,雌性通过卵黄IgY提供母体免疫力.
结论:
- A. galli 感染会导致家禽的重大病理变化和经济损失.
- 主体免疫反应,特别是2型免疫,对于控制A. galli至关重要,尽管自然获得的免疫需要进一步定义.
- 了解宿主-寄生虫相互作用对于开发有效的防治策略对中虫病至关重要.
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