在患有疼痛性糖尿病外围神经病变的患者中,混杂器治疗的有效性:单臂前性试点研究
Seung Hee Yoo1, Won-Joong Kim1, Ji Seon Chae2
1Department of Anesthesiology and Pain Medicine, College of Medicine, Ewha Womans University, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
Medicine
|September 29, 2023
概括
斯克兰布勒疗法 (ST) 显示了对疼痛性糖尿病外围神经病变 (DPN) 的短期疼痛缓解. 然而,DPN管理的长期有效性仍然有限,在治疗后的一个月之后没有发现显著改善.
科学领域:
- 神经学 神经学
- 疼痛管理 疼痛管理
- 糖尿病神经病变 - 糖尿病神经病变
背景情况:
- 疼痛性糖尿病外围神经病变 (DPN) 是一个重要的管理挑战.
- 对DPN进行神经调节技术的探索,但从前性试验中缺乏证据.
- 编码器治疗 (ST) 尚未对疼痛的DPN进行前性评估.
研究的目的:
- 调查混疗法 (ST) 在治疗疼痛性糖尿病外围神经病变 (DPN) 的长期疗效.
主要方法:
- 患者进行了10次连续的ST疗程 (每次45分钟),持续时间为1-2天.
- 主要结局:在多个时间点评估的视觉模拟量表 (VAS) 疼痛评分.
- 二次结果:MNSI,塞姆斯-温斯坦测试和利兹评估得分在基线和后续评估.
主要成果:
- 在ST治疗期间和治疗后长达1个月观察到显著的VAS疼痛评分改善.
- 在ST感染1个月后,MNSI自我报告得分下降.
- 没有其他测量结果显示出与基线的统计学上显著差异.
结论:
- 编码器疗法 (ST) 可能为痛苦的DPN提供暂时的缓解.
- 对于疼痛性DPN,ST的长期益处似乎有限.
- 需要进一步的研究来确定ST在DPN中的持续有效性.
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