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Updated: Jul 15, 2025

Author Spotlight: Using a Rabbit Model to Explore the Efficacy of Tuina in Treating Knee Osteoarthritis
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膝关节骨关节炎的成年人抵抗训练的剂量反应关系:系统性审查和元分析

Huan Wang1, Baoan Ma1, Guotuan Wang2

  • 1Department of Orthopedics, Tangdu Hospital of Air Force Military Medical University, Xi'ep, China.

Journal of geriatric physical therapy (2001)
|September 29, 2023
PubMed
概括

抵抗训练 (RT) 显著改善膝关节骨关节炎 (KOA) 症状,功能和肌肉力量. 经过4到8周的RT观察到最优的益处,突出其治疗潜力.

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Agonists can bind with and activate receptors, resulting in the formation of drug-receptor complexes. Once formed, these complexes catalyze many biochemical processes at the cellular level and subsequently induce a pharmacologic response. The degree of response is directly proportional to the fraction of activated receptors, which in turn, depends on the concentration of the drug at the receptor site as well as the sensitivity of the receptor. An increase in the administered dose contributes to...
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Dose-Response Relationship: Selectivity and Specificity

Drugs exert their therapeutic effects by interacting with receptors, enzymes, or ion channels that are present throughout the human body. The strength and duration of the interaction between a drug and its target receptor are characterized by the selectivity and specificity of the drug. Selectivity refers to a drug's strong preference for its intended target over other targets. For instance, isoprenaline, a non-selective β-adrenergic agonist, interacts with both β1- and...
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