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心力衰竭患者的肠道微生物群概况:系统性审查
Daniel Martin Simadibrata1, Salwa Auliani2, Putu Ayu Widyastuti3
1Faculty of Medicine Universitas Indonesia, Jakarta, Indonesia; Nuffield Department of Population Health (NDPH), University of Oxford, Oxford, United Kingdom. . daniel.simadibrata@lmh.ox.ac.uk.
Journal of gastrointestinal and liver diseases : JGLD
|September 29, 2023
概括
与健康个体相比,心力衰竭患者表现出改变的肠道微生物群,有益细菌减少. 这种肠心轴连接突出显示了微生物组.
科学领域:
- 微生物学 微生物学
- 心脏病学 心脏病学
- 胃肠病学 胃肠病学
背景情况:
- 传统的心血管风险因素是已知的心力衰竭 (HF) 的预测因素.
- 肠心轴表明肠道微生物群和心血管系统之间的相互作用,可能诱导炎症并导致HF.
- 本综述探讨了肠道微生物组与HF之间的相互联系.
结论:
- 肠道微生物群的多样性,丰富性和组成在肝炎患者和健康人群之间存在显著差异.
- 短链脂肪酸 (SCFA) 生产肠道细菌在HF患者中被耗尽.
- 潜在的并发症,环境,生活方式和饮食可以影响HF的肠道微生物群异质性.
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