在炎症性肠病中,基于疾病接受和感知控制的患者细分的外部有效性和随时间的一致性
Liselot Willemijn Van Erp1, Pepijn Wa Thomas2, Marcel Jm Groenen3
1Crohn and Colitis Centre, Department of Gastroenterology and Hepatology, Rijnstate Hospital, Arnhemm, The Netherlands. lvanerp@rijnstate.nl.
Journal of gastrointestinal and liver diseases : JGLD
|September 29, 2023
概括
一种针对炎症性肠病 (IBD) 的新型患者细分模型有效预测与健康相关的生活质量 (HRQoL). 这种基于疾病接受和控制的模型,显示出随着时间的推移的外部有效性和一致性,指导个性化的IBD护理.
科学领域:
- 胃肠病学 胃肠病学
- 精神病体医学是一种精神病体医学.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 炎症性肠病 (IBD) 患者的护理可以使用细分模型来个性化.
- 这个模型根据疾病接受和感知到的控制来对患者进行分类.
- 这个模型的外部有效性和时间一致性需要调查.
研究的目的:
- 调查IBD患者细分模型的外部有效性.
- 评估这个模型随着时间的推移的一致性.
- 确定患者群体与与健康相关的生活质量 (HRQoL) 之间的关联.
主要方法:
- 一项多中心纵向队列研究,涉及成年IBD患者.
- 调查问卷评估了疾病接受,感知控制和HRQoL.
- 根据接受度和对照分数,患者被划分为四组.
主要成果:
- 细分模型证明了外部有效性和内部一致性.
- 分段在人口统计,疾病持续时间,药物和活动方面存在显著差异.
- 接受/控制较高的细分市场与接受/控制较低的细分市场相比,显示出明显更好的HRQoL.
结论:
- 患者细分模型是外部有效的,并随着时间的推移保持一致.
- 患者细分独立地与IBD中的HRQoL相关.
- 干预措施应通过针对疾病接受和感知控制来个性化IBD护理.
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