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Updated: May 12, 2026

DNA Methylation: Bisulphite Modification and Analysis
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以甲基核酸为基础的向蛋白酶使得甲基-CpG结合蛋白2的向降解成为可能

Zhen Wang1, Jing Liu1, Xing Qiu2

  • 1Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, United States.

Journal of the American Chemical Society
|September 29, 2023
PubMed
概括

研究人员开发了向甲基蛋白溶解的嵌合体 (甲基-PROTACs) 来降解癌细胞中的甲基-CpG结合蛋白2 (MeCP2),为表观遗传向提供了新的治疗策略.

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