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实时时空地图监测系统的成本效益,用于预防耐美西林的金黄色葡萄球菌
Y Cai1, E C Philips2, S Arora2
1Programme in Health Services and Systems Research, Duke-NUS Medical School, Singapore.
The Journal of hospital infection
|September 29, 2023
概括
4D-Disease Outbreak Surveillance System (4D-DOSS) 显示了对耐美西林黄金葡萄球菌 (MRSA) 监测的潜在成本效益. 建议对MRSA成本进行进一步的研究,以减少模型不确定性.
科学领域:
- 卫生经济学 卫生经济学
- 传染病监测 传染病监测 传染病
- 数字健康数字健康
背景情况:
- 一个新的基于数字双胞胎的感染监测系统,4D-Disease Outbreak Surveillance System (4D-DOSS) 正在新加坡开发中.
- 该系统旨在提供近乎实时的感染监测和映射.
- 甲素耐药黄金葡萄球菌 (MRSA) 被选为本研究的模型病原体.
研究的目的:
- 评估4D-DOSS对MRSA监测的潜在成本效益.
- 将采用4D-DOSS的经济影响与当前的监控实践进行比较.
- 确定影响系统成本效益的关键参数.
主要方法:
- 开发了一个马尔科夫模型来模拟MRSA殖民和感染的30天时间,每天循环.
- 该模型从医院的角度评估了成本效益.
- 进行了概率敏感性分析,场景分析和信息价值分析.
主要成果:
- 在基本情况 (零实施成本) 中,4D-DOSS具有68.6%的成本效益概率.
- 在100万美元的实施成本和效率降低的场景中,成本效益的概率下降到47.7%.
- 与MRSA相关成本的不确定性被确定为模型不确定性的主要驱动因素.
结论:
- 该研究确定了在当前的支付意愿值下,4D-DOSS可能具有成本效益的条件.
- 建议对特定参数进行进一步研究,以减少模型不确定性.
- 建议将该系统扩展到包括其他耐药生物体,以进行全面评估.
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