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激活BMP4-pSmad1/5通路会损害内动脉瘤中VSMCs的功能

Luojiang Zhu1, Haishuang Tang1, Congyan Wu1

  • 1Neurovascular Centre, Changhai Hospital, Naval Medical University (Second Military Medical University), Shanghai 200433, China.

Vascular pharmacology
|September 29, 2023
PubMed
概括

骨形态遗传蛋白4 (BMP4) 在内动脉瘤 (IA) 中升高,促进血管光滑肌细胞 (VSMC) 亡和增殖. 这种BMP4信号通路失调有助于IA的发展,并提供了潜在的治疗点.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.骨形态遗传蛋白质 4 骨形态遗传蛋白质 4内动脉瘤 内动脉瘤现象型转变的变化血管光滑肌细胞是血管光滑肌细胞

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