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艾滋病毒暴露前预防使用模式的动态性和与MSM执行的坚持相关的关系:香港的一项实施研究

Ngai Sze Wong^1,2,3, Denise Pui-Chung Chan^1,2, Tsz Ho Kwan^1,2,3

¹Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Hong Kong, China.

AIDS and behavior

|September 29, 2023

概括

对暴露前预防 (PrEP) 的高度坚持对于与男性发生性关系的男性 (MSM) 的艾滋病毒预防至关重要. 这项研究确定了各种PrEP使用模式,突出了对坚持策略的需求,特别是对于偶尔使用者.

科学领域:

公共卫生公共卫生
预防传染病预防传染病
性健康性的健康

背景情况:

暴露前预防 (PrEP) 在与男性发生性关系的男性 (MSM) 中有效预防艾滋病毒.
保持高 PrEP 坚持对于有效的艾滋病毒预防至关重要.
了解PrEP使用模式对于实施研究至关重要.

研究的目的:

检查香港MSM中PrEP使用模式.
评估PrEP使用模式和预防有效遵守 (EA) 之间的关联.
确定促进PrEP使用者遵守规则的策略.

主要方法:

在香港进行了一年的前性实施研究,涉及312个MSM.
数据收集包括艾滋病毒检测,肌素检测,咨询和PrEP补充.
隐性类分析被用来识别基于日记记录测量执行的坚持 (EA) 的prep用户模式.

主要成果:

在研究队列中没有观察到艾滋病毒突破性感染.
在215名拥有日记记录的MSM中,执行遵守 (EA) 的中位数为89%.
确定了三种不同的PrEP使用者类别:每日主导的,偶发的和混合的时间表,具有不同的性活动和坚持水平.

结论:

在香港的MSM中,PrEP的使用模式是多样化和动态化的.
插曲性PrEP使用者表现出较低的坚持,需要有针对性的坚持支持.
促进持续高坚持的战略对于在MSM群体中有效预防艾滋病毒至关重要.

关键词:

坚持的坚持坚持的坚持艾滋病病毒艾滋病病毒艾滋病病毒与男性发生性关系的男性.暴露前预防暴露前预防性行为性行为.

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