患有PCOS的女性的性功能障碍:一个病例对照研究
H Pastoor1, S Both2, E T M Laan2
1Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, Erasmus University Medical Centre, Rotterdam, The Netherlands.
Human reproduction (Oxford, England)
|September 30, 2023
概括
患有多囊性卵巢综合征 (PCOS) 的女性经历更多的性功能障碍和痛苦. 然而,性类固醇水平对这些女性的性功能产生了最小的直接影响.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 性医学性医学性医学性医学
- 内分泌学 在内分泌学.
背景情况:
- 患有多囊性卵巢综合征 (PCOS) 的女性报告说,性功能和满意度降低,性困扰增加.
- 导致这种情况的因素包括肥胖,,,不孕不育,焦虑和抑郁.
- 在PCOS中常见的过高雄激素和性功能之间的关系仍然是不确定的.
研究的目的:
- 为了研究性类固醇水平与PCOS和没有PCOS的女性的性功能之间的关系.
- 为了比较PCOS和对照组女性之间的性功能和痛苦水平.
主要方法:
- 一项观察性前性病例控制研究,涉及135名年龄在18-40岁的女性 (68名患有PCOS,67名对照).
- 参与者接受了广泛的医疗和内分泌查,包括质谱和验证的性功能问卷.
- 数据是在2017年3月至2020年3月期间收集的.
主要成果:
- 与对照组相比,患有PCOS的女性报告性功能显著降低 (FSFI),性困扰更高 (FSDS-R),性功能障碍和临床性困扰率更高.
- 回归分析显示,雄激素水平与性功能之间的关联很少且很弱,最多解释了15%的差异.
- 虽然组激素相互作用是显著的,但单独的分析显示PCOS组没有显著的关联;对照组显示某些雄激素和性功能参数之间的弱负相关性.
结论:
- 在患有PCOS的女性中,性功能受损,但内分泌因素似乎对直接影响最小.
- 对于患有PCOS的女性的临床护理应解决性问题,并提供心理性咨询.
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