睡眠变化,进食时间变化,以及早期成年期的动脉内膜-介质厚度
Elissa K Hoopes1, Melissa A Witman1, Michele N D'Agata1
1College of Health Sciences University of Delaware Newark DE.
Journal of the American Heart Association
|September 30, 2023
概括
不一致的睡眠和饮食时间表与年轻成年人脑内动脉内膜介质厚度 (CIMT) 的增加有关,这是早期动脉样硬化的一个标志. 睡眠时间和时间的更大变化,以及进食中点,预测了更高的CIMT.
科学领域:
- 心血管健康 心血管健康
- 睡眠科学 睡眠科学
- 营养科学 营养科学
背景情况:
- 由于睡眠和饮食模式变化的循环节律障碍与心脏代谢风险有关.
- 睡眠和饮食变化与亚临床动脉样硬化之间的关联仍未得到充分研究.
研究的目的:
- 在健康成年人中研究睡眠模式的变化和饮食时间与亚临床动脉样硬化标志物之间的关系.
主要方法:
- 14天的睡眠和饮食评估使用加速计和摄影辅助饮食记录.
- 使用标准偏差对睡眠时间,睡眠开始,饮食开始,饮食偏差和热量中点进行量化变化.
- 通过对共变量进行调整的回归模型,评估了与动脉内膜介质厚度 (CIMT) 的关联.
主要成果:
- 睡眠持续时间 (SD) 和睡眠开始 (SD) 的变化增加与更大的CIMT显著相关.
- 热量中点 (SD) 的变化增加也与更大的CIMT有关.
- 睡眠变化指标显示,与CIMT的关联比食用时间变化更强.
结论:
- 睡眠模式和饮食时间的变化与CIMT增加有关,CIMT是亚临床动脉样硬化的一个生物标志物.
- 这些发现凸显了成年早期持续睡眠和饮食行为对心血管健康的临床相关性.
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