瑞典学龄儿童中阿托皮性皮炎的流行率下降:三次重复的基于人口的调查
Maja Af Klinteberg1, Anna Winberg2, Martin Andersson3
1Department of Public Health and Clinical Medicine, Dermatology and Venereology, Umeå University, Umeå, Sweden.
The British journal of dermatology
|September 30, 2023
概括
在2006年至2017年期间,瑞典学龄儿童中亚型皮肤炎 (AD) 的患病率显著下降. 然而,喘等相关的过敏状况显著增加,引发了公众健康的担忧.
科学领域:
- 儿科 儿科 儿科
- 流行病学 流行病学
- 过敏学 过敏学
背景情况:
- 全球范围内,特别是高收入国家,亚托皮炎 (AD) 的患病率有所上升,约20%的儿童受到影响.
- 最近的趋势表明,在高收入国家,阿尔茨海默病患病率可能会停滞不前.
研究的目的:
- 检查瑞典学龄儿童中阿尔茨海默病患病率和相关的亚托皮性并发症的趋势.
- 通过使用来自多个队伍的数据来分析随时间的变化.
主要方法:
- 瑞典诺尔博顿的一项基于人口的研究,涉及三组学龄儿童 (1996年,2006年,2017年).
- 使用了基于国际儿童喘和过敏研究 (ISAAC) 协议的相同问卷.
- 使用ISAAC标准和医生诊断的AD (D-AD) 来评估AD患病率.
主要成果:
- 阿尔茨海默病的患病率从1996年的22.8%下降到2017年的16.3% (P < 0.001).
- 医生诊断的AD (D-AD) 也下降了,从9.3%降至5.7% (P < 0.001).
- 同时喘患病率从1996年的12.2%显著增加到2017年的23.0% (P < 0.001). 过敏性鼻炎和敏感性表现出最初的增加,然后平稳下来.
结论:
- 在研究期间,瑞典学童的阿尔茨海默病患病率下降.
- 在患有阿尔茨海默症的儿童中,亚托皮性并发症,特别是喘,显著增加.
- 尽管下降,但阿尔茨海默病仍然很常见,并且伴随疾病的增加值得关注.
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