后缺氧状态 - 状态的一个独特的亚型,预后不佳
Kateriine Orav1,2, Pilar Bosque Varela1, Tanja Prüwasser1,3
1Department of Neurology, Member of the European Reference Network EpiCARE, Centre for Cognitive Neuroscience, Christian Doppler University Hospital, Paracelsus Medical University of Salzburg, Salzburg, Austria.
Epileptic disorders : international epilepsy journal with videotape
|September 30, 2023
概括
心脏骤停后缺氧性脑损伤后的状态 (SE) 表明预后不佳. 不同类型的SE,包括电图,电临床和眼膜-眼膜间连续体,表现出类似的不良结果.
科学领域:
- 神经学 神经学
- 关键护理医学 关键护理医学
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 心脏骤停 (CA) 后的低毒性脑损伤可能导致后低毒性状态 (SE).
- 在这种患者群体中,临床结果和特定的SE类型需要进一步阐明.
研究的目的:
- 评估可能和确定的后低氧性SE.患者的临床结果.
- 描述在绝对后低氧性SE患者中观察到的不同类型的SE.
主要方法:
- 预期招募可能或确定的SE后CA.患者.
- 间歇性EEG用于SE诊断,由盲目评估者对SE模式和背景EEG特征进行后期分析.
- 根据ILAE语义的最终SE分类,死亡率和大脑性能类别 (CPC) 在1个月后进行评估.
主要成果:
- 在64名被纳入的患者中观察到高达92%的死亡率.
- 只有一个幸存者取得了良好的神经结果 (CPC 1),属于阴茎 - 阴茎间连续体 (IIC) 组.
- 在EEG上没有观察到爆发抑制,低电压或电脑静音的生存;SE被诊断为CA后47小时的中位数.
结论:
- 缺氧性脑损伤后的后缺氧性SE与严重的预后有关.
- 在电图SE,电临床SE和IIC之间没有发现显著的结果差异.
- 在最终的电图SE中存在或缺少突出的电机特征并没有显著地改变结果.
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