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Updated: Jul 15, 2025

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LDLR和PCSK9 3'UTR变异及其对家族高胆固醇血症中微RNA分子相互作用的假定影响:一种计算方法

Renata Caroline Costa de Freitas1,2, Raul Hernandes Bortolin1,3, Jessica Bassani Borges4

  • 1Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of Sao Paulo, Av. Prof. Lineu Prestes, 580. São Paulo, Sao Paulo, 05508-000, Brazil.

Molecular biology reports
|September 30, 2023
PubMed
概括

与FH相关基因的3'未翻译区域的变异,特别是LDLR和PCSK9,破坏了miRNA相互作用,可能与家族性高胆固醇血清症的分子诊断有关.

关键词:
3UTR变体的变体家庭性高胆固醇血症是什么?在形分析中进行了分析.这就是LDLR的LDLR.在PCSK9中.mRNA:miRNA 相互作用

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