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使用共聚焦显微镜评估大脑内皮细胞的紧张结合完整性

Himakarnika Alluri1, Chander Sekhar Peddaboina2, Binu Tharakan3

  • 1Precision for Medicine, Redwood City, CA, USA.

Methods in molecular biology (Clifton, N.J.)
|September 30, 2023
PubMed
概括

血脑屏障是血液与大脑之间的屏障.

关键词:
血液-大脑屏障是什么?紧密结合蛋白质是紧密结合的蛋白质.佐努拉封闭-1 免疫光体f-actin 的使用情况.

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Tight Junctions01:29

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Tight junctions are molecular seals between cells that prevent the leaking of fluids, ions, and other small solutes across cavities and compartments in multicellular organisms. They are mainly composed of claudin and occludin transmembrane proteins, and other proteins such as tricellulin and JAM (junctional adhesion molecule). All these proteins are 4-pass transmembrane proteins, except JAM, which is a single-pass transmembrane protein belonging to the immunoglobulin superfamily. The...
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