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宫外 adrenocorticotropic 激素 (ACTH) 综合征:两个病例报告
Ting Huang1, Yanyan Zhang1, Yigang Wang2
1Department of Endocrinology, Panzhihua Central Hospital, Panzhihua, 617067 China.
Neuro endocrinology letters
|September 30, 2023
概括
宫外 adrenocorticotropic 激素 (ACTH) 综合征 (EAS) 的诊断是具有挑战性的. 聚子发射断层扫描-计算机断层扫描 (PET-CT) 有助于识别主要病变,早期控制高皮质醇症可以预防感染.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 宫外 adrenocorticotropic 激素 (ACTH) 综合征 (EAS) 呈现出由于隐藏的初级病变的诊断挑战.
- 及时诊断和治疗EAS对于患者的治疗结果至关重要.
- 本文详细介绍了两个具有挑战性的EAS案例,提供诊断和治疗见解.
研究的目的:
- 为了呈现出两例异位腺上皮质激素 (ACTH) 综合征 (EAS) 的病例.
- 为了分享对EAS的诊断和治疗的见解.
- 要突出PET-CT在EAS中识别初级病变的实用性.
主要方法:
- 根据病史和辅助检查,评估了两名疑似EAS的成年患者.
- 在一个患者身上进行了手术干预 (上腺切除术).
- 用正子发射断层扫描-计算机断层扫描 (PET-CT) 和胸部CT扫描用于病变识别.
- 一名患者的病情由于并发症而恶化,阻止了进一步的诊断程序.
主要成果:
- 案例1:PET-CT在腺腺切除术后发现了甲状腺瘤转移的初级神经内分泌瘤.
- 案例2:胸部CT显示肺结节和中间腺淋巴病变;然而,肺活检是不可行的.
- 病例2最终死于严重的肺部感染.
结论:
- 阳位子发射断层扫描 - 计算机断层扫描 (PET-CT) 是异位 adrenocorticotropic hormone (ACTH) 综合征 (EAS) 的有效诊断工具.
- 迅速管理高皮质醇症对于减轻EAS患者危及生命的感染风险至关重要.
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