多视图图谱网络学习框架,用于识别严重抑郁症.
Mengda Zhang1, Dan Long2, Zhaoqing Chen1
1School of Automation, Hangzhou Dianzi University, Hangzhou, China.
Computers in biology and medicine
|September 30, 2023
概括
大型抑郁症 (MDD) 诊断使用一种新的多视图神经网络 (MV-GNN) 进行了改进,该网络分析了大脑的功能连接. 这种人工智能模型整合了拓和空间大脑数据,在识别MDD患者时达到65.61%的准确性.
科学领域:
- 神经科学是一个神经科学.
- 人工智能的人工智能
- 医疗成像医学成像
背景情况:
- 休息状态功能磁共振成像 (rs-fMRI) 揭示了与重大抑郁障碍 (MDD) 相关的非欧几里德拓结构的功能连接 (FC).
- 现有的方法很难将FC的各种结构信息整合到全面的MDD诊断中.
研究的目的:
- 开发一种新的层次学习结构,即多视图神经网络 (MV-GNN),以改进MDD患者的识别.
- 整合来自FC的拓和空间结构信息,以获得更强大的诊断模型.
主要方法:
- MV-GNN从拓视图中过并重建FC,使用各种值来识别关键大脑区域属性.
- 一种双离开一个错过的交叉特征选择方法从均大小的FC结构中提取空间视图信息.
- 图形卷积神经网络和自我注意力图形聚合用于高效的嵌入,与关机制融合拓和空间视图.
主要成果:
- 通过离开一个站点的交叉验证,MV-GNN在单个中心的网站上识别MDD患者的平均准确率达到65.61%.
- 该模型在MDD识别方面,与最先进的方法相比,表现优越.
- 从多个角度揭示了MDD和健康对照 (HC) 组之间的信息差异.
结论:
- 拟议的MV-GNN有效地整合了多视图FC数据,以加强MDD诊断.
- 该模型为客观诊断MDD提供了有价值的歧视性信息.
- 这种方法可以作为理解MDD病理基础的参考.
更多相关视频
10:43Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
Published on: July 1, 2014
15.2K
08:51Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
Published on: November 1, 2019
5.7K
相关概念视频
Depressive Disorders: MDD and Dysthymia
149
Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
149
Depressive Disorders: Etiology
114
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
114
Depression: Overview
271
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
271
Long-term Depression
2.6K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
Calcium Ion Concentration Mechanism
If over...
2.6K
Bipolar Disorder
78
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
78
Introduction to Psychological Disorders
409
Abnormal behavior, often referred to as mental illness, results from changes in brain function that influence thought patterns, behaviors, and social interactions. Psychologists and psychiatrists typically assess abnormal behavior using three primary criteria: deviance, maladaptation, and personal distress, particularly when these traits persist over long periods.
Deviant Behavior
Deviance in behavior refers to actions or thought patterns that significantly diverge from societal norms or...
Deviant Behavior
Deviance in behavior refers to actions or thought patterns that significantly diverge from societal norms or...
409
