儿童的非反流性主要大尿路从近端到远端分辨
Harkanwal Randhawa1, Conor Jones1, Melissa McGrath2
1Division of Urology, Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
Urology
|September 30, 2023
概括
在儿童中,非反流性主要大尿道 (NRPM) 的自发解决通常从近位向远位进展. 远端尿路扩张可能比近端片段需要长达10个月的时间才能解决.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 医疗成像医学成像
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 非反流性原发性大尿道 (NRPM) 是一种先天性疾病,其特征是尿道扩张而没有囊尿道反流.
- 了解NRPM的自然史和解决模式对于适当的患者管理和监测至关重要.
- 产前水 (HN) 是一个常见的发现,NRPM是其潜在原因之一.
研究的目的:
- 评估诊断为NRPM的儿童尿管扩张的自发解决.
- 为了确定分辨率的模式,特别是它是否发生近距离到远距离或远距离到近距离.
主要方法:
- 从产前水缩数据库 (0-24个月) 中确定了92名NRPM儿童的前队列.
- 排除标准包括先前的手术,不到6个月的随访,或没有空白的囊回形图 (VCUG).
- 尿道段 (近端,中端,远端) 根据胎儿泌尿学会 (SFU) 的分级,前后直径 (APD) 和尿道直径,使用描述统计和卡普兰-梅尔曲线来分析分辨率.
主要成果:
- 在66名符合条件的患者中,76%的人显示出整体HN分辨率.
- 解析率因尿道段不同而有所不同:近道段为83%,中道段为72%,远道段为33%.
- 与近位和中位相比,远位尿路段的分辨率明显较慢 (P < .01).
结论:
- 在儿童中,NRPM的自发解决通常是从近端到远端的进展.
- 距离泌尿管扩张需要更长的解决期,可能比近端段长10个月.
- 这些发现有助于预测NRPM的自然过程和管理患者的期望.
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