患有莫亚莫亚病的成年人的记忆,执行和智力功能
Naoki Maehara1, Akira Nakamizo1, Koichi Arimura1
1Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
World neurosurgery
|September 30, 2023
概括
记忆功能与成年人患有莫亚莫亚病 (MMD) 的执行和智力能力有关. 额头评估电池 (FAB) 可能有助于选MMD患者的记忆问题.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 认知科学 认知科学
背景情况:
- 认知能力下降,特别是记忆力下降,对于患有莫亚莫亚病 (MMD) 的成年人来说是令人担忧的.
- 在MMD中,记忆,执行功能和智力能力之间的相互作用尚未得到充分理解.
- 在MMD中脑血流与记忆之间的直接关系尚不清楚.
研究的目的:
- 研究MMD成年人的记忆,执行功能和智力功能之间的相关性.
- 探索MMD成年人的脑血流和记忆之间的关联.
主要方法:
- 31名患有MMD的成年人接受了对记忆 (韦克斯勒记忆量表修订,WMS-R),执行功能 (正面评估电池,FAB) 和智力功能 (韦克斯勒成人智力量表,WAIS) 的评估.
- 使用123的I-胺单光子发射计算机断层扫描来测量大脑血流.
主要成果:
- WMS-R得分与FAB和WAIS得分在重血管化前和后都有显著的相关性.
- 在左后脑动脉区域的脑血流与WMS-R和WAIS分数正相关.
- 在特定的大脑区域 (小脑,pons,vermis) 的术后脑血管储备与视觉和一般记忆有关.
结论:
- 记忆功能与MMD成年人的执行和智力功能相互关联.
- 鉴于其短时间的服用时间,FAB可以作为MMD中记忆功能障碍的有用查工具.
- 在MMD中,记忆缺陷可能与后脑动脉区域的低输液有关,手术后脑血管储备可以预测记忆结果.
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