非腹膜十二指腺瘤的冷内切除:系统性审查和聚合分析
Marco Spadaccini1, Ludovico Alfarone1, Antonio Facciorusso2
1Humanitas University, Department of Biomedical Sciences, 20072 Pieve Emanuele, Italy; Humanitas Clinical and Research Center -IRCCS-, Endoscopy Unit, 20089 Rozzano, Italy.
概括
冷陷切除是一种安全有效的方法,用于去除非腹膜十二指肠病变. 这种技术显著减少了与热陷方法相比的不良事件,为十二指甲骨病变管理提供了有前途的方法.
科学领域:
- 胃肠病学 胃肠病学
- 内視鏡外科手術 內視鏡外科手術
- 在瘤学瘤学.
背景情况:
- 对于非腹膜十二指肠病变,正在出现冷陷技术,旨在减少不良事件 (AE).
- 十二指肠的薄薄的血管壁对电术提出了独特的挑战,加剧了AE的担忧.
研究的目的:
- 系统地审查和汇集关于冷陷切除十二指肠病变的疗效和安全性的数据.
- 评估与此技术相关的不良事件,完全切除和复发率.
主要方法:
- 在Medline,Scopus和EMBASE的系统文献搜索到2023年1月.
- 从11项涉及233名患者的3137个非腹膜十二指肠病变的研究中对11项研究的数据进行了综合分析.
- 随机效应模型用于分析不良事件,完全切除和复发率.
主要成果:
- 对于冷陷切除的整体不良事件率很低,为0.25%.
- 完全切除率高达99.40%,残留/复发率为12.95%.
- 损伤大小被确定为影响不良事件和复发风险的重要因素.
结论:
- 冷陷切除证明了高效率和一个优秀的安全性概况,非腹膜十二指肠病变.
- 这种技术似乎是热陷方法的可行和安全的替代方案,特别是考虑到十二指肠解剖学.
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