烧伤患者的抗生素管理模式:一项TrinetX研究
Kendall Wermine1, Sunny Gotewal1, Juquan Song2
1School of Medicine, University of Texas Medical Branch, Galveston, TX, USA.
Burns : journal of the International Society for Burn Injuries
|September 30, 2023
概括
在烧伤患者中,抗生素的使用率在老年人中较高,并且通常发生在受伤当天. 青素和β-乳酸盐是最常见的,根据烧伤严重程度没有显著差异.
科学领域:
- 医学研究 医学研究
- 烧伤护理 烧伤护理
- 抗生素耐药性 抗生素耐药性
背景情况:
- 抗生素耐药性是越来越令人担忧的,但在烧伤患者中,明确的处方模式仍未确定.
- 这项研究调查了一大批烧伤患者的抗生素处方趋势.
研究的目的:
- 分析美国内烧伤患者的抗生素处方模式.
- 确定影响抗生素在烧伤护理中的患者特定因素.
主要方法:
- 利用TrinetX数据库识别受伤患者,在受伤7天内接受全身抗生素.
- 按年龄,时间间隔 (2004-2019) 和受伤后的时间,以及%的总表面积烧伤 (%TBSA) 分层的患者.
- 在统计学意义上使用了千二测试 (p<0.05) 和在相关性方面使用了皮尔森系数.
主要成果:
- 年长的烧伤患者比年轻的患者更频繁地服用抗生素.
- 绝大多数 (87.6%) 的抗生素处方是在受伤当天发生的.
- 青素和β-乳糖抗菌药物是最常被处方的 (64%),无论TBSA燃烧的百分比如何.
结论:
- 提供了对美国烧伤护理当前抗生素处方实践的见解.
- 增强对这一群体中历史和当代抗生素使用模式的理解.
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