IGF1R-化PYCR1促进ELK4的转录活性,并维持瘤在低氧条件下的生长

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Updated: Jul 15, 2025

Induction and Testing of Hypoxia in Cell Culture
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Induction and Testing of Hypoxia in Cell Culture

Published on: August 12, 2011

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Ke Zheng1,2, Nannan Sha2, Guofang Hou2

  • 1Department of Radiotherapy, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, China.

Nature communications
|September 30, 2023
PubMed
概括

在缺氧下,IGF1R的核酸化促进了瘤生长. 这种PYCR1活动调节基因转录,并与结直肠癌恶性有关.

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