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Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Updated: Jul 15, 2025

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

Published on: February 25, 2022

通过4D流动MRI进行插曲时间优化的大动脉脉冲波速估计.

Sungho Park^1,2,3, Minseong Kwon¹, Hyojin Nam¹

¹Daegu-Gyeongbuk Medical Innovation Foundation, Medical Device Development Center, Daegu, 41061, South Korea.

Scientific reports

|September 30, 2023

概括

四维流磁共振成像 (4D流MRI) 脉冲波速度 (PWV) 测量得到了改善,关键的插值时间 (Crit). 这种方法减少了体外差异,并保持了心血管疾病查的体内准确性.

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科学领域:

生物医学工程生物医学工程
心血管成像 - 心血管成像
医学物理医学物理

背景情况:

四维流磁共振成像 (4D流MRI) 能够通过脉冲波速度 (PWV) 估计进行区域大动脉硬度的非侵入性评估.
流波形状的变化可能会影响4D流PWV测量的准确性,需要对最佳参数进行调查.
了解这些变异对于使用4D流PWV的可靠心血管疾病查至关重要.

研究的目的:

为了研究插值时间 (iT) 对4D流量PWV测量的影响.
提出和验证一个关键插值时间 (iT_Crit),以平衡精度和计算效率.
在幽灵和人体研究中,将 iT_Crit 与传统方法进行比较.

主要方法:

4D流 PWV 值是使用交叉相关算法计算的,其插值时间有所变化.
在体外研究中使用了灵活和硬的幻影模型来确定关键的 iT (iT_Crit).
在体内研究中,在6名健康志愿者中,将iT_Crit与1毫秒的常规iT (iT_{1毫秒) 进行了比较.}

主要成果:

拟议的iT_Crit将体外4D流量PWV值的平均差异减少19%,与iT_{1 ms}相比.
使用 iT_Crit进行的体内测量显示出与 iT_{1 ms}获得的差异相似.
开发了一个差异估计模型,以根据已知的PWV和iT值预测PWV差异.

结论:

临界插值时间 (iT_Crit) 为4D流量PWV估计提供了改进的方法,提高了幻影研究的准确性.
iT_Crit提供了与常规方法相比的体内结果,表明其临床适用性.
这项研究有助于更好地了解受生理因素和波形采集参数影响的PWV变异.