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慢性病中的抗凝药:目前的状况和未来的前景
Alfred Jones1, Dawn Swan1, Ton Lisman2
1Department of Haematology, Beaumont Hospital, Dublin, Ireland.
Journal of thrombosis and haemostasis : JTH
|October 1, 2023
概括
在慢性病 (CKD) 患者中管理血栓是复杂的. 本综述研究了心房动和静脉血栓栓塞症的CKD患者的安全抗凝策略,平衡出血和凝血风险.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心脏病学 心脏病学
- 血液学 血液学 血液学
背景情况:
- 慢性病 (CKD) 的患病率正在全球范围内上升.
- 慢性病患者经常有并发症,增加了血栓形成和出血的风险.
- 口服抗凝剂对于预防中风和静脉血栓塞栓症至关重要,但在CKD中具有挑战性.
研究的目的:
- 审查CKD患者当前使用抗凝剂的情况.
- 为CKD患者提供安全抗凝剂的实用建议.
- 在这个人群中解决出血和血栓栓塞风险之间的平衡.
主要方法:
- 对CKD当前抗凝剂使用的文献综述.
- 对关于CKD抗凝剂的临床证据的分析.
- 综合数据,制定实际建议.
主要成果:
- 抗凝剂的益处在CKD中不太明显,原因是出血和凝血风险增加.
- 慢性瘤复杂化了心房动和静脉血栓栓塞的管理.
- 最佳的抗凝策略需要仔细考虑个体患者的因素.
结论:
- 在CKD中安全的抗凝剂需要一个细微的方法.
- 提供了建议,以帮助临床医生为抗凝固CKD患者做出决策.
- 在CKD管理中,平衡血栓和出血风险至关重要.
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