孕产妇高氧化对新生儿后果的影响 在患有病态心脏病图的分娩妇女中:一项开放式随机对照试验
Sruthy P Sulaiman1, Nivedita Jha1, Adhisivam Bethou2
1Department of Obstetrics and Gynecology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
American journal of obstetrics and gynecology
|October 1, 2023
概括
高氧疗法没有改善新生儿阿普加尔分数在分娩妇女与有关胎儿心率模式. 尽管剖腹产分娩率较低,但这种干预措施并没有有利于新生儿的结果.
科学领域:
- 产科 产科 产科 产科 产科
- 新生儿护理 新生儿护理
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 过氧化显示出在分娩期间改善可疑胎儿心脏模式的潜力.
- 它对新生儿发育结果在病态胎儿心率追踪的病例的影响仍然没有研究.
研究的目的:
- 为了评估80%的微分吸入氧气 (FiO2) 与40%的FiO2对新生儿结局的影响.
- 专注于妇女经历劳动与病态胎儿心率跟踪.
主要方法:
- 随机,开放标签,盲人评估者临床试验在第三级护理医院.
- 包括一个月的单项怀孕,宫扩张≥6厘米和病态胎儿心率跟踪 (根据FIGO 2015指南).
- 干预: 10升/分钟氧气通过非再呼吸面罩; 常规护理: 6升/分钟通过简单的面罩,直到绳紧.
主要成果:
- 两组之间5分钟Apgar评分 (9对9;P=.12) 的中位数没有显著差异.
- 相比的新生儿重症监护室入院率 (9.5%对12.2%;P=.6) 和需要正压通风 (6.8%对8.1%;P=.75).
- 在高氧化组中,剖腹产的发生率显著降低 (4.1%对25.7%;P=.00) 和下静脉的马隆迪化物水平 (P=.00).
结论:
- 高氧化 (80% FiO2) 在患有病态胎儿心率追踪的妇女中没有改善新生儿Apgar分数.
- 新生儿重症监护室的入院率和带血气体参数在两组之间是可比的.
- 在这种患者群体中,高FiO2补充对新生儿结局没有明显的好处.
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