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Updated: Jul 15, 2025

NF-κB-dependent Luciferase Activation and Quantification of Gene Expression in Salmonella Infected Tissue Culture Cells
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NF-κB-dependent Luciferase Activation and Quantification of Gene Expression in Salmonella Infected Tissue Culture Cells

Published on: January 12, 2020

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印萨帕多克-桑提取物通过NF-κB p65通路激活产生增强免疫力的效果

Gyuwon Huh1,2, Youngse Oh3, Youngsic Jeon1

  • 1Natural Product Research Center, Korea Institute of Science and Technology, Gangneung 25451, Republic of Korea.

BioMed research international
|October 2, 2023
PubMed
概括

伊桑帕多克桑提取物 (ISE) 激活巨细胞,促进免疫反应,如氧化和炎症性细胞因子. 这种免疫激活是通过核因子-kappa B (NF-κB) 信号通路进行的.

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Immunostimulatory Agent Evaluation: Lymphoid Tissue Extraction and Injection Route-Dependent Dendritic Cell Activation

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相关概念视频

NF-κB-dependent Signaling Pathway02:26

NF-κB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
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An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
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