在虫患者皮肤细菌菌群的概况
Srujana Mohanty1, Swarnatrisha Saha1, Shehnaz Firdaus1
1Department of Microbiology, All India Institute of Medical Sciences Bhubaneswar, Bhubaneswar, Odisha, India.
Journal of laboratory physicians
|October 2, 2023
概括
皮肤细菌感染在虫患者中很常见,金黄色葡萄球菌是最常见的病原体. 监测这些感染对于选择有效的抗微生物治疗和降低死亡率至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 微生物学 微生物学
- 传染性疾病 传染性疾病
背景情况:
- ,一种自身免疫性水泡性疾病,由于二次机会性感染,具有很高的死亡风险.
- 皮肤细菌感染的pemphigus病变可以导致严重的并发症和增加死亡率.
研究的目的:
- 为了研究皮肤细菌感染的频谱,在尾虫患者.
- 确定孤立病原体的抗微生物敏感性模式.
- 为及时诊断和治疗虫相关感染的治疗策略提供信息.
主要方法:
- 在两年内 (2018年7月 - 2020年6月) 从虫患者收集气/样.
- 进行了标准的微生物培养技术和抗菌素敏感性测试.
- 数据分析遵循临床和实验室标准研究所的指导方针.
主要成果:
- 从211个培养阳性样本中 (在315名患者中) 确定了245个细菌分离物.
- 黄金葡萄球菌 (56.3%) 是主要的分离物,其次是Pseudomonas aeruginosa (16.7%) 和大肠杆菌 (6.5%).
- 发现了显著的抗菌素耐药性,包括S. aureus中24.6%的甲素耐药性和9.5-14.6%的格拉姆阴性细菌中卡巴胺耐药性.
结论:
- 皮肤细菌感染是尾虫管理中的一个重要问题.
- 多种耐药生物的流行需要谨慎监测.
- 根据敏感性测试进行适当的抗微生物治疗选择对于改善患者的治疗结果至关重要.
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