在线指导体育活动培训对老年人认知和肠-大脑轴相互作用的影响:随机对照试验的协议
Simon J Schrenk1, Stefan Brodoehl1, Stefano Flor2
1Department of Neurology, Jena University Hospital - Friedrich Schiller University of Jena, Jena, Germany.
Frontiers in aging neuroscience
|October 2, 2023
概括
这项研究调查了为期8周的体育活动计划如何影响老年人的认知功能,大脑健康和肠道微生物群. 这些发现可能揭示了促进健康认知衰老的机制.
科学领域:
- 老年学是指老年学的学科.
- 神经科学是一个神经科学.
- 微生物组研究 微生物组研究
背景情况:
- 全球人口老龄化需要健康的认知老龄化策略.
- 身体活动是对认知衰退的一种有前途的干预措施,但机制尚不清楚.
- 了解这些机制是制定有效的健康促进计划的关键.
研究的目的:
- 为了检查8周的身体活动干预对健康老年人的认知功能,大脑结构/功能和肠道屏障功能的影响.
- 探索认知,大脑和微生物组参数变化之间的关系.
- 提供对身体活动对认知健康的益处的生物学基础的见解.
主要方法:
- 随机对照试验与100名健康参与者 (60-75岁).
- 干预组:为期8周的多组分体育活动计划 (基于在线).
- 对照组:为期8周的放松计划 (基于在线).
- 评估包括神经认知测试,脑成像,身体健康,以及在基线和干预后的肠道微生物组概况.
主要成果:
- 主要结果是从基线到干预后视觉处理速度的变化.
- 二次结果包括对认知,大脑和微生物组数据的探索性分析.
- 该研究将分析观察到的变化之间的相互关系.
结论:
- 这项研究旨在阐明结构化的体育活动计划对老年人的认知,神经和肠道健康的影响.
- 预计结果将为提高认知功能和促进健康衰老的策略提供信息.
- 这项研究有助于理解体育活动的多方面的好处.
更多相关视频
07:01Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
Published on: September 20, 2020
4.8K
07:27Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
Published on: October 6, 2016
10.3K
相关概念视频
Cognitive Development During Adulthood
142
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
142
Physiology of Enteric Nervous System and Gut Health
294
The gastrointestinal tract, responsible for the digestion and absorption of nutrients, is safeguarded by the intestinal barrier, which consists of secretory, physical, and immune components. At the forefront is the secretory barrier, composed of essential elements such as mucus, gut microbiota, and defense proteins. They collaborate to break down food particles, facilitate nutrient absorption, and maintain optimal gut health. These secretory components ensure the smooth functioning of the...
294
