摄入量和多种与健康相关的结果:对分析的总体综述
Puze Wang1, Bo Chen1, Yin Huang1
1Department of Urology, West China Hospital, Sichuan University, Chengdu, China.
Frontiers in nutrition
|October 2, 2023
概括
是一种必不可少的微量元素,显示出混合的健康益处. 虽然它可以降低某些癌症的风险,并改善PCOS等疾病,但由于证据质量不佳和潜在风险,不建议用于一般人群.
科学领域:
- 营养科学 营养科学
- 公共卫生 公共卫生
- 证据综合 证据综合
背景情况:
- 是一种重要的微量金属元素,对人类健康至关重要.
- 了解摄入对健康的全面影响至关重要.
研究的目的:
- 进行总体审查,评估有关摄入量和健康结果的证据质量.
- 评估现有系统审查和元分析中的有效性和识别偏见.
主要方法:
- 系统搜索和批判性评价已公布的系统评价,并使用聚合数据和元分析.
- 证据评估侧重于质量,有效性和潜在的偏见.
主要成果:
- 摄入与消化系统癌症的风险降低有关,所有原因的死亡率,抑郁症,Keshan疾病和儿童的Kashin-Beck疾病.
- 补充剂可以改善精子质量,PCOS,自身免疫性甲状腺疾病,心血管健康和感染性结果.
- 2型糖尿病和非黑色素瘤皮肤癌的潜在风险增加;证据质量大多被评为低.
结论:
- 有限的证明优势和低质量的证据表明,一般人群不应常规补充.
- 一旦缺乏状态得到纠正,请停止服用补充剂.
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