在急性缺血性中风患者中,急性便秘的成像和临床预测因素
I Joon Han1, Ji-Eun Lee2, Ha-Na Song2
1Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Frontiers in neuroscience
|October 2, 2023
概括
急性缺血性中风可能导致便秘,通常与胰岛和前中心状圈等区域的双边脑损伤有关. 最初的中风严重程度和血液标志物也可以预测便秘的发展.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 医学研究 医学研究
背景情况:
- 在急性缺血性中风患者中,便秘很常见.
- 对于中风后便秘的预测因素尚不清楚.
- 这项研究调查了与急性便秘相关的临床和神经成像因素.
研究的目的:
- 为了确定与缺血性中风后急性便秘相关的特定大脑病变.
- 确定急性缺血性中风患者便秘的临床和实验室预测因素.
主要方法:
- 基于医院的中风注册表 (2018-2019) 的分析.
- 检查临床,实验室和神经成像特征.
- 使用基于多变量支持向量的回归的损伤症状映射 (SVR-LSM).
主要成果:
- 在256名患者中,有81名患者 (32%) 经历了急性便秘.
- 最初的中风严重程度 (NIHSS分数) 和血栓栓塞性标记 (FDP,D-二次体,自由脂肪酸) 与便秘有关.
- 胰岛,前中心,下侧叶的双边病变与便秘有显著的联系.
结论:
- 经过缺血性中风的急性便秘与双边岛屿,前中心和下侧叶损伤有关.
- 最初的神经缺陷的严重程度和特定的血液标记是关键的临床预测指标.
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