左束枝节奏保持左心室心肌工作在患有胸心的患者
Huang-Chung Chen1, Wen-Hao Liu1, Yung-Lung Chen1
1Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung, Taiwan.
Frontiers in cardiovascular medicine
|October 2, 2023
概括
在患有高节奏负担的患者中,左枝节奏 (LBBP) 保持了左心室 (LV) 肌动脉工作 (MW) 比右心室节奏 (RVP) 和非选择性的His-bundle节奏 (NS-HBP) 更好. 这一发现表明LBBP可能是一个更生理化的节奏选择.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 心脏机械学 心脏机械学
背景情况:
- 左捆枝节奏 (LBBP) 是一种新兴的生理节奏方法.
- 左心室 (LV) 心肌工作 (MW) 评估心肌收缩性,但其对LBBP的反应是未知的.
- 这项研究研究了LBBP对胸肌病患者的LV MW的影响.
研究的目的:
- 为了评估LBBP对LV心肌工作 (MW) 的影响,在患有胸节律不良的患者中.
- 为了比较LBBP,非选择性His-bundle节奏 (NS-HBP) 和右心室节奏 (RVP) 之间的LV MW.
主要方法:
- 预期招募70名患有正常 LV 缩功能的胸肌病患者.
- 分类为LBBP (n=46),NS-HBP (n=24),RVP (n=16) 和对照 (n=10) 组.
- 使用2D斑点跟踪心声学对LV压力-应变环的非侵入性评估,以计算全球LVMW.
主要成果:
- 6个月后,LBBP的>40%心室节奏显示出较高的全球MW指数,建设性工作和效率,与RVP和NS-HBP相比.
- 与RVP和NS-HBP组相比,LBBP组显示出更高的LV全球纵向菌株.
- 与RVP和NS-HBP组相比,LBBP组的全球浪费工作较低.
结论:
- 在中期高节奏负担 (> 40%) 的患者中,LBBP比NS-HBP和RVP更有效地保持LV心肌工作 (MW).
- LBBP可能代表一个更生理的节奏策略.
- 需要进一步的研究来将LV MW与高节奏负担的LBBP患者的长期临床结果相关联.
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