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Updated: Jul 15, 2025

Stimulation of Cytoplasmic DNA Sensing Pathways In Vitro and In Vivo
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更新了cGAS-STING信号在自身免疫性疾病中的作用

Ya Liu1,2, Feifei Pu2,3

  • 1Department of Rheumatology and Immunology, Traditional Chinese and Western Medicine Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Frontiers in immunology
|October 2, 2023
PubMed
概括

干扰素基因 (cGAS-STING) 途径的循环GMP-AMP合成酶刺激器对自然免疫至关重要,但其过度激活与自身免疫性疾病有关. 了解这种途径为与炎症相关的疾病提供了新的治疗途径.

关键词:
自身免疫性疾病 自身免疫性疾病cGAS-STING信号传输系统提供信号.这是一种炎症炎症炎症炎症.自然免疫力是一种自然的免疫力.这是一种I型干扰子.

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