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Updated: Jul 15, 2025

Dissection of Enhancer Function Using Multiplex CRISPR-based Enhancer Interference in Cell Lines
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基因组背景使监管要素对遗传破坏变得敏感

Raquel Ordoñez1,2, Weimin Zhang1,2, Gwen Ellis1,3

  • 1Institute for Systems Genetics, NYU School of Medicine, New York, NY 10016, USA.

bioRxiv : the preprint server for biology
|October 2, 2023
PubMed
概括

研究增强器功能需要了解基因组背景. 这项研究使用了Big-IN技术来分析Igf2/H19位,揭示了取决于环境的增强剂活性和以前未知的调控元素.

关键词:
增强选择性 增强选择性基因调节 基因调节 基因调节基因工程是基因工程,是基因工程.基因组写作 基因组写作基因组监管架构 基因组监管架构合成调节基因组学 合成调节基因组学

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