多巴胺神经元发射的预期相关变化取决于海马
Yuji K Takahashi1, Zhewei Zhang1, Marlian Montesinos-Cartegena1
1Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD.
bioRxiv : the preprint server for biology
|October 2, 2023
概括
轨道前皮层 (OFC) 和海马体 (HC) 都有助于创建灵活行为的认知地图. HC病变扰乱了估计长期任务状态,与影响短期预测的OFC病变不同.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
背景情况:
- 轨道前皮层 (OFC) 和海马体 (HC) 对于认知或任务地图的形成至关重要,支持灵活的行为.
- 多巴胺神经元已被用作传感器来评估OFC病变对认知映射的功能影响.
结论:
- OFC和HC在认知映射中发挥着不同的作用,OFC处理局部,试验特定的信息,HC管理更长时间的抽象状态.
- 多巴胺神经元整合来自各种大脑区域的信息,包括OFC和HC,关于环境的预测结构.
- 多巴胺神经元的这种集成可能通过强大的教学信号支持复杂的学习和行为.
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