过敏敏感化的患病率和危险因素:从1996年到2017年,在学校儿童中进行了3项横截面研究
Eva Rönmark1, Joakim Bunne1, Anders Bjerg2
1Division of Sustainable Health, Department of Public Health and Clinical Medicine, The OLIN Unit, Umeå University, Umeå.
The journal of allergy and clinical immunology. Global
|October 2, 2023
概括
从1996年至2006年,儿童的过敏敏感性增加,然后稳定下来. 风险因素保持一致,但与喘和过敏性鼻炎 (AR) 的关联有所不同,表明疾病管理的变化.
科学领域:
- 儿科 儿科 儿科
- 免疫学 免疫学 免疫学
- 流行病学 流行病学
背景情况:
- 北欧地区过敏敏感性和疾病的流行率不断上升,需要更新研究.
- 瑞典北部儿童过敏的最新流行病学数据缺乏.
研究的目的:
- 调查瑞典北部儿童中过敏敏感性流行趋势的趋势.
- 识别与过敏敏感性相关的风险因素.
- 检查过敏敏感化与喘和过敏性鼻炎 (AR) 之间的关联.
主要方法:
- 1996年,2006年和2017年对三个儿童队列 (7-8岁) 的截面研究.
- 用10种空气中的过敏原进行皮肤刺伤测试 (SPT).
- 对风险因素和疾病关联进行调整的波桑回归分析.
主要成果:
- 总体而言,过敏敏感化患病率从21% (1996年) 增加到30% (2006年),并在2017年稳定下来.
- 家庭过敏史是一个一致的风险因素;在家里养猫是保护性的.
- 喘患病率增加,但其与敏感性的联系减弱;AR患病率下降,但其与敏感性的联系加强.
结论:
- 2006年以后,儿童过敏敏感性趋于平稳,风险因素稳定.
- 喘和AR关联的不同趋势表明,过敏性疾病的临床管理正在发展.
相关概念视频
Allergic Reactions
27.7K
Overview
27.7K
Asthma-I: Introduction
2.7K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.7K
Asthma-II: Pathophysiology and Classification
2.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.7K
Asthma: Pathogenesis and Management
433
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
433
Attention-Deficit/Hyperactivity Disorder
85
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
85
Allergic Drug Reactions
873
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
873


