慢性鼻炎与鼻和过敏性鼻炎作为喘中的不同多病可治疗特征
José Antonio Castillo1,2,3, Vicente Plaza4, Gustavo Rodrigo5
1Pneumology Department, Hospital Universitari Dexeus, Barcelona, Spain.
The journal of allergy and clinical immunology. Global
|October 2, 2023
概括
严重的喘与具有鼻息肉的慢性鼻炎 (CRSwNP) 有关,影响喘控制. 过敏性鼻炎 (AR) 和CRSwNP是关键的上呼吸道特征,需要进一步研究以更好地治疗喘.
科学领域:
- 呼吸系统医学 呼吸系统医学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 免疫学 免疫学 免疫学
背景情况:
- 喘经常与上呼吸道多病症有关.
- 过敏性鼻炎 (AR) 与早期过敏性喘有关.
- 具有鼻息肉的慢性鼻炎 (CRSwNP) 与晚期非过敏性喘有关.
研究的目的:
- 调查喘严重程度和控制与特定上呼吸道表型之间的关联.
- 为了确定影响喘管理的上呼吸道可治疗的特征.
主要方法:
- 预计将从肺病学和耳鼻喉科诊所招募492名喘患者.
- 使用国际共识指南评估喘严重程度,控制和上呼吸道并发症 (AR,NAR,CRSwNP,CRSsNP).
- 包括多重物流回归在内的统计分析.
主要成果:
- 49.6%的患者患有鼻炎 (37.0%的AR,12.6%的NAR) 和36.2%的患者患有CRS (16.7%的CRSsNP,19.5%的CRSwNP).
- 在严重喘 (35%) 和非托普性喘 (44%) 中,CRSwNP的发生率更高.
- 严重的喘与CRSwNP显示控制较差,与鼻占用相关;晚发喘,NSAID不耐受性,和CRSwNP独立预测严重的喘.
结论:
- 严重的喘与CRSwNP显著相关,而鼻占用会对喘控制产生负面影响.
- 在喘中,AR和CRSwNP代表着不同的,可治疗的上呼吸道表型.
- 进一步评估AR和CRSwNP对于改善喘管理和患者结果至关重要.
更多相关视频
03:40Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
Published on: December 20, 2024
532
06:34A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
Published on: June 4, 2017
10.1K
相关概念视频
01:26Asthma-II: Pathophysiology and Classification
2.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.7K
01:29Asthma-I: Introduction
2.7K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.7K
01:20Asthma: Pathogenesis and Management
433
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
433
01:25Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
326
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
326
01:24Asthma-III: Symptoms and Complications
2.5K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
2.5K
01:30Asthma-IV: Diagnostic and Management
2.5K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.5K