机器学习的方法用于从电子健康记录中提取现实世界的数据变量
Blythe Adamson1,2, Michael Waskom1, Auriane Blarre1
1Flatiron Health, Inc., New York, NY, United States.
Frontiers in pharmacology
|October 2, 2023
概括
使用自然语言处理 (NLP) 和机器学习 (ML) 的人工智能 (AI) 可以有效地将电子健康记录 (EHR) 编辑成用于瘤学研究的现实世界数据 (RWD).
科学领域:
- 在瘤学瘤学.
- 医疗信息学 医疗信息学
- 人工智能的人工智能
背景情况:
- 人工智能的进步,包括像ChatGPT这样的NLP和ML模型,为EHR数据策划创造了新的可能性.
- 电子健康记录 (EHR) 的高效选为现实数据 (RWD) 对于瘤学的证据生成至关重要.
- 促进对EHR数据的AI方法的透明度和可解释性是一个新兴的研究领域.
研究的目的:
- 描述人工智能驱动的EHR数据策划行业方法的研究和开发.
- 促进人工智能在现实世界数据生成中的应用透明度和可解释性.
主要方法:
- 应用NLP和ML技术来训练,验证和测试从非结构化EHR文档中提取信息.
- 利用全国范围的EHR衍生数据库进行研究.
- 专注于基于机器学习的,仅由模型决定的变量提取,而不预测未来事件或推断缺失的信息.
主要成果:
- 开发并验证了一种NLP/ML方法,用于从非结构化的EHR数据中提取临床上有意义的信息.
- 与手动抽象数据相比,在提取的变量中实现了高性能.
- 生成的研究准备变量包括癌症诊断,阶段,组织学,吸烟状态,手术,生物标志物结果和治疗方法.
结论:
- 通过NLP和ML,可以快速且可扩展地从电子健康记录中提取回顾性临床数据.
- 这种方法有助于研究人员从癌症患者的经验中学习.
- 人工智能驱动的数据策划增强了对瘤学研究现实数据的实用性.
相关概念视频
01:30Methods of Documentation VII: EMR
855
Electronic Medical Records (EMRs) primarily center around electronically documenting patients' health information within a single healthcare organization or practice. They contain essential clinical data related to a patient's medical history, diagnoses, medications, treatment plans, lab results, and other pertinent information relevant to the specific encounter or episode of care. EMRs are designed to streamline documentation and workflow processes within individual healthcare...
855
01:20Biostatistics: Overview
265
Biostatistics plays a crucial role in understanding and analyzing data in healthcare and biology. Biostatisticians conduct experiments, gather evidence, and draw meaningful conclusions using statistical methods and techniques. Different variables form the foundation of biostatistical analysis, allowing researchers to understand and interpret data effectively. These variables are classified into different types, each serving a specific purpose in statistical analysis.
Discrete variables are...
Discrete variables are...
265
01:29Issues And Trends In Healthcare Delivery System
5.7K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.7K
01:23Mechanistic Models: Compartment Models in Individual and Population Analysis
64
Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
64
01:12What is an Experiment?
11.7K
An experiment is a planned activity carried out under controlled conditions. The purpose of an experiment is to investigate the relationship between two variables. When one variable causes change in another, we call the first variable the explanatory or independent variable. The affected variable is called the response or dependent variable. In a randomized experiment, the researcher manipulates values of the explanatory variable and measures the resulting changes in the response variable. The...
11.7K
01:18Steps in Outbreak Investigation
152
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
152