夜班工作和血清标记器的骨循环在男性轮班工人
Margherita Martelli1, Gianmaria Salvio2, Raffaella Lazzarini1
1Occupational Health, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, Italy.
Chronobiology international
|October 2, 2023
概括
夜班工作可能会增加男性的骨质疏松症风险. 在夜班工作者中观察到较高的骨周转标记 (CTX和P1NP),表明潜在的骨健康问题.
科学领域:
- 职业健康 职业健康 职业健康
- 内分泌学 在内分泌学.
- 骨的新陈代谢 骨的新陈代谢
背景情况:
- 夜班工作与睡眠障碍,昼夜节律障碍和维生素D不足有关,所有这些都会影响骨质.
- 骨周转率标志物,如I型原蛋白的C端端片段 (CTX) 和I型原蛋白的N端 (P1NP),可以评估骨周转率.
研究的目的:
- 为了评估CTX,P1NP和25-氧维生素D的血清水平在男性夜班工作者.
- 评估与日间工人相比,男性轮班工人骨质疏松症的潜在风险.
主要方法:
- 测量了CTX,P1NP和25-氧维生素D的血清水平.
- 研究了82名男性受试者:42名白天工人和40名夜班工人.
主要成果:
- 与日班工人相比,夜班工人表现出CTX和P1NP的血清水平显著更高.
- 两组之间没有发现25-基维生素D水平的显著差异.
结论:
- 夜班工人中CTX和P1NP水平升高表明骨周转率较高.
- 这表明男性夜班工人骨质疏松症风险可能增加.
- 需要对夜班男工的骨健康进行进一步的研究.
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