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Updated: Jul 20, 2026

In Vitro Aggregation Assays Using Hyperphosphorylated Tau Protein
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甲基衍生物紫的剂量依赖的结合行为与衍生物原纤维素相互作用

Xiaoxiao Wu1, Lili Zhu1,2, Gang Wang1

  • 1Key Laboratory of Exercise and Health Sciences (Ministry of Education), Shanghai Frontiers Science Research Base of Exercise and Metabolic Health, and School of Exercise and Health, Shanghai University of Sport, 399 Changhai Road, Shanghai 200438, China. qianzhenyu@sus.edu.cn.

Physical chemistry chemical physics : PCCP
|October 2, 2023
PubMed
概括

紫蛋白在阿尔茨海默氏症模型中破坏PHF6纤维细胞核. 这项研究揭示了紫素对聚的剂量依赖的结合和抑制作用,为药物开发提供了洞察力.

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Allosteric Proteins-ATCase01:19

Allosteric Proteins-ATCase

Binding sites linkages can regulate a protein's function.  For example, enzyme activity is often regulated through a feedback mechanism where the end product of the biochemical process serves as an inhibitor.
Aspartate transcarbamoylase (ATCase) is a cytosolic enzyme that catalyzes the condensation of L-aspartate and carbamoyl phosphate to  N-carbamoyl-L-aspartate. This reaction is the first step in pyrimidine biosynthesis. UTP and CTP, the end products of the pyrimidine synthesis pathway,...