母亲围产期抑郁症状的发展轨迹预测了幼儿早期的执行功能
Josephine Power1, Stuart Watson1,2, Wai Chen3,4,5,6,7,8,9
1School of Clinical Sciences, Department of Psychiatry, Monash University, Clayton, VIC, Australia.
Psychological medicine
|October 2, 2023
概括
怀孕期间和产后产妇的抑郁症状与4岁儿童执行功能 (EF) 较差有关. 即使考虑到像吸烟或酒精这样的产前暴露,这种关联仍然存在.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 围产期心理健康 围产期心理健康
背景情况:
- 围产期母亲抑郁会影响胎儿的神经发育.
- 潜在的间接影响包括母亲吸烟,饮酒或使用抗抑郁药.
- 这些风险因素对儿童执行功能 (EF) 的具体影响需要进行系统的调查.
研究的目的:
- 确定母亲抑郁症诊断和母亲抑郁症状 (MDS) 的轨迹是否预测孩子在4岁时的EF.
- 探索吸烟,酒精和抗抑郁药的使用对儿童的间接影响EF.
- 分析围产期MDS和儿童EF结果之间的关系.
主要方法:
- 对197名妇女及其子女进行的前性妊娠队列研究.
- 潜在生长曲线建模用于分析从怀孕到产后12个月的MDS轨迹.
- 在4岁时使用学前年龄精神病学评估,NEPSY-II和Shape School任务评估儿童EF.
主要成果:
- 随着时间的推移,MDS的增加预测了儿童更多的注意力缺失症状,更差的切换和运动抑制.
- 在调整为母亲的认知和教育后,MDS和儿童注意力缺失症状之间的关联仍然很重要.
- 被诊断为抑郁症和产前暴露 (吸烟,酒精,抗抑郁药) 并没有预测儿童EF结果或调解抑郁症状的影响.
结论:
- 在产前期增加的孕产妇抑郁症状与4岁时儿童EF较差有关.
- 这种关联独立于产前吸烟,饮酒或使用抗抑郁药.
- 抑郁症的慢性,严重程度和产后因素可能会显著影响儿童EF结果.
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