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Updated: Jul 15, 2025

Author Spotlight: Investigating the Motion Dynamics of the Eukaryotic Replisome Components at the Single-Molecule Level
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在哺乳动物细胞周期中,DONSON对于CMG酶组合是必需的

Cecile Evrin1, Vanesa Alvarez2, Johanna Ainsworth1

  • 1The MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK.

EMBO reports
|October 2, 2023
PubMed
概括

唐森蛋白对于哺乳动物染色体复制至关重要,因为它在S相期间确保了CDC45-MCM-GINS合酶的组装. 它的缺失破坏了DNA复制,解释了它与梅尔-戈林综合征的联系.

关键词:
在CMG中使用 CMG Helicase.复制DNA复制DNA复制DNA复制唐森·唐森是什么意思梅尔 - 戈林综合征 (Meier-Gorlin综合征) 是一种启动 启动 启动

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M cyclin...
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