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Updated: Jun 16, 2026

Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog
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Published on: November 5, 2014

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针对有机离子输送聚1A2,1B1,1B3和2B1开发的基于光的竞争性反流试验确定了胺素是选择性的OATP1A2基质

Orsolya Ungvári1,2, Éva Bakos1, Daniella Kovacsics1

  • 1Institute of Enzymology, RCNS, Eötvös Loránd Research Network, Budapest, Hungary.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology
|October 2, 2023
PubMed
概括

有机离子运输多 (OATPs) 对于药物运输至关重要. 一种新的基于光的测定方法将OATP基质与抑制剂区分开来,将胺素确定为OATP1A2基质.

关键词:
血脑屏障是什么意思毒品运输公司OATP基于光的测试方法.肝脏 肝脏 肝脏 肝脏 肝脏 肝脏这种药物是 pentamidine.毒性的毒性 毒性的毒性

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Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions08:31

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The pharmacogenetics of drug transporters is increasingly recognized as a critical factor influencing interindividual variability in drug absorption, distribution, and elimination. These membrane-bound proteins regulate drugs' movement across cellular barriers by actively pumping them out (efflux) or facilitating their uptake (influx). Among the major transporter families, ATP-binding cassette (ABC) and solute carrier (SLC) transporters play particularly prominent roles. Genetic polymorphisms...