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Updated: Jul 15, 2025

Author Spotlight: A Bicelle Crystallization Setup for ABC Transporter Membrane Proteins to Advance Drug Development
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在ABC蛋白质中估计了前水解向外状态的真实稳定性

Márton A Simon1,2,3, Iordan Iordanov1,2,3, Andras Szollosi1,2,3

  • 1Department of Biochemistry, Semmelweis University, Budapest, Hungary.

eLife
|October 2, 2023
PubMed
概括

确定了囊性纤维化转膜导电调节器 (CFTR) 离子通道的非水解性闭合率. 破坏ATP水解的突变揭示了CFTR中核酸结合域界面的独特特征.

关键词:
这是一个D-循环.复合ATP-结合部位是复合的ATP结合部位.闪 关闭 关闭分子生物物理学分子生物物理学突变周期的突变周期结构生物学结构生物学异国主义者 (Xenopus) 是斑马鱼是一种斑马鱼.

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