高度脏损伤的非手术治疗:一个系统的审查协议
Silas Nann1,2, Molly Clarke1, Shivangi Jog3
1JBI, The University of Adelaide, Adelaide, SA, Australia.
JBI evidence synthesis
|October 2, 2023
概括
本系统性审查将预防性栓塞与成人严重脏损伤的临床观察进行比较. 这些发现将指导治疗高度脏创伤的治疗决策.
科学领域:
- 创伤外科 手术 创伤外科
- 干预性放射学 干预性放射学
- 手术结果研究研究.
背景情况:
- 脊髓损伤在创伤后很常见,死亡率很高.
- 对于稳定的患者,非手术治疗是标准的,但对高度损伤的预防性栓塞仍然存在争议.
研究的目的:
- 为了确定血栓塞是否比观察更有效,对于患有III-V级脏损伤的成年患者.
- 为了告知临床实践和未来的研究管理严重的脏创伤.
主要方法:
- 系统性审查和对比预防性栓塞和对形骨创伤的临床观察的研究的元分析.
- 在PubMed,Embase,CINAHL,试验注册表和灰色文献中进行搜索.
- 使用JBI工具重复数据提取和质量评估,并对结果进行GRADE评估.
主要成果:
- 分析的结果包括死亡率,治疗失败,ICU入院,住院和输血需求.
- 统计元分析将在可能的情况下使用随机效应模型进行.
- 该审查旨在提供两种管理策略的最终比较.
结论:
- 该审查将建立基于证据的指导,以最佳管理高度脏损伤.
- 研究结果将澄清预防性栓塞在改善患者治疗结果中的作用.
- 这项研究解决了创伤护理中的一个关键争议.
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