在老年患者中,手术期间体温和硫醇/二硫化物平衡之间的关系,这些老年患者接受了带脊髓麻醉的可选横尿道前列腺切除手术
L Kazancioglu1, S Batcik, M Arpa
1Department of Anesthesiology and Reanimation, Medical Faculty, Recep Tayyip Erdogan University, Rize, Turkey. leyla.kazancioglu@erdogan.edu.tr.
在手术期间保持体温对于老年患者至关重要. 监测和变暖可以帮助减少氧化应激,改善醇/二硫化物平衡,防止低温的潜在并发症.
科学领域:
- 麻醉学 麻醉学
- 老年医学 老年医学
- 生物化学 生物化学
背景情况:
- 外科手术期间的低温是接受手术的老年患者的一个风险.
- 醇/二硫化物平衡是氧化应激的标志物.
- 通过尿道切除前列腺是老年人常见的选择性手术.
研究的目的:
- 为了研究手术期间体温与醇/二硫化物平衡之间的关系.
- 评估老年患者在手术期间氧化应激标志物的变化.
主要方法:
- 研究了71名老年患者 (ASA I-II),这些患者在脊髓麻醉下接受了选择性通过尿道切除前列腺.
- 对核心体温进行监测.
- 硫化物/硫化物平衡参数 (总硫化物,原生硫化物,硫化物,比率) 在手术前和手术期间进行测量.
主要成果:
- 与手术前相比,二硫化物水平在手术期间显著增加 (p<0.001).
- 氧化应激标志物 (二硫化物/原生硫醇,二硫化物/总硫醇) 在手术期间更高.
- 原生硫醇/总硫醇的比率在手术期间下降.
- 发现了硫醇水平与患者年龄之间的相关性.
结论:
- 在手术期间的低温可能会对醇/二硫化物平衡产生负面影响,这表明氧化应激增加.
- 建议定期监测体温和加热技术,以减轻外科手术期间低温的风险.
- 控制体温可能有助于减少老年手术患者的氧化应激.
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