综合系统性炎症指数与重症的存在和严重程度之间的关系
S B Yıldırım1, K I Ayaydın Yılmaz, N B Altuntaş
1Department of Obstetrics and Gynecology, Faculty of Medicine, Giresun University, Giresun, Turkey. iclal_itf@hotmail.com.
系统性炎症指数,如系统性炎症反应指数 (SIRI),在重症 (HG) 中升高,与疾病严重程度相关. SIRI显示出强大的诊断潜力,用于HG的存在和严重程度.
科学领域:
- 产科和妇科 产科和妇科
- 免疫学 免疫学 免疫学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 妊娠中症 (HG) 是一种严重的怀孕中恶心和吐的形式.
- 了解HG的潜在炎症过程对于诊断和管理至关重要.
研究的目的:
- 为了确定 HG 患者的全身炎症标志物水平.
- 调查这些标志物与HG严重程度之间的关联.
- 评估他们对HG的诊断潜力.
主要方法:
- 与83名HG患者和100名健康孕妇对照进行了比较.
- 计算了中性粒细胞与淋巴细胞的比率 (NLR),血小板与淋巴细胞的比率 (PLR),全身免疫炎症指数 (SII),全身炎症反应指数 (SIRI) 和总体全身炎症指数 (AISI).
- 根据严重程度分组HG患者,使用修改后怀孕独特量化吐/恶心 (PUQE) 评分.
主要成果:
- 在HG患者中,NLR,PLR,SII,SIRI和AISI显著更高.
- 这些指数随着HG严重程度的增加而增加.
- 在SIRI中,HG存在 (AUC:0.695) 和严重程度 (AUC:0.785) 的诊断性能最高.
结论:
- 综合系统性炎症指数与HG的存在和严重程度有关.
- 这些指数作为HG的独立风险因素.
- SIRI是对HG及其严重程度的最强大的诊断工具.
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