结肠直肠癌查收据在老年人中不存在10年死亡风险差异
Po-Hong Liu1, Amit G Singal1, Caitlin C Murphy2
1Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
The American journal of gastroenterology
|October 2, 2023
概括
在65-84岁的成年人中,结肠直肠癌 (CRC) 查率不会因预测的10年死亡风险而变化. 目前的基于年龄的查可能会导致健康的老年人治疗不足,而患有慢性疾病的年轻人治疗过度.
科学领域:
- 老年学是一门学科.
- 预防医学 预防医学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 评估健康状况和预期寿命对于评估老年人结直肠癌 (CRC) 查计划至关重要.
- 目前的CRC查指南主要关注年龄,可能忽视个人健康状况和预期寿命.
研究的目的:
- 检查预测10年死亡风险与65-84岁社区成年人CRC查收到的相关性.
- 评估在预期寿命小于10年的个体中进行的CRC查的比例.
主要方法:
- 分析了来自国家健康访谈调查的25888名65-84岁的成年人的数据,这些成年人没有最新的CRC查.
- 利用经过验证的指数来估计10年死亡风险,将参与者分为五分之一.
- 检查了死亡风险五分之一的查患病率,并评估了预期寿命小于10年的查.
主要成果:
- 过去一年的CRC查患病率在10年死亡风险五分位数 (最低至最高:39.5%至35.4%) 中没有显著差异.
- 在最低和最高死亡风险五分之一之间,CRC查的几率没有差异 (aOR1.05).
- 显著的查比例 (27.9%) 发生在<10年预期寿命的个体中,超过一半的老年人 (75-84岁) 具有≥50%的10年死亡风险.
结论:
- 目前基于年龄的CRC查实践与预测的10年死亡风险不一致.
- 基于年龄的方法可能会导致健康的老年人的低选和患有并发症的年轻人过度选.
- 个性化CRC查包括个人预期寿命可以提高查计划的价值和效率.
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